{"id":361,"date":"2022-02-08T11:19:08","date_gmt":"2022-02-08T10:19:08","guid":{"rendered":"https:\/\/ern-ithaca.eu\/?post_type=expert-centers&p=361"},"modified":"2025-06-11T13:54:22","modified_gmt":"2025-06-11T11:54:22","slug":"ern-ithaca-brussels-center-erasme","status":"publish","type":"expert-centers","link":"https:\/\/ern-ithaca.eu\/de\/about-us\/expert-centers\/ern-ithaca-brussels-center-erasme\/","title":{"rendered":"ERN-ITHACA \u2013 Br\u00fcssel-Zentrum"},"content":{"rendered":"
\"\"<\/figure>\n\n\n\n

Centre de g\u00e9n\u00e9tique humaine \u2013 ULB
Service de G\u00e9n\u00e9tique M\u00e9dicale \u2013 H\u00f4pital Erasme
Erasme Hospital \u2013 ULB
Route de Lennik 808
1070 BRUSSELS
BELGIEN<\/p>\n\n\n\n

\n
Website<\/a><\/div>\n<\/div>\n\n\n\n

Blei<\/h2>\n\n\n\n
\n
\n
\"\"<\/figure>\n<\/div>\n\n\n\n
\n

Pr Catheline VILAIN<\/strong><\/p>\n\n\n\n

Telefon<\/strong>: +32 (0)2 555 64 30<\/p>\n\n\n\n

Fax<\/strong>: +32 (0)2 555 64 40<\/p>\n\n\n\n

E-Mail<\/strong>: genmed@erasme.ulb.ac.be<\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n

Geltungsbereich<\/h2>\n\n\n\n

Das Fachgebiet unseres Zentrums als Mitglied des europ\u00e4ischen Referenznetzwerks (ERN) \u201eITHACA\u201c umfasst alle Syndrome, die mit Entwicklungsst\u00f6rungen und\/oder einer geistigen Behinderung (ID) einhergehen. Etwa 1 von 40 Neugeborenen weist eine angeborene Fehlbildung auf (261 von 10.000 F\u00f6ten und Neugeborenen laut EuroCAt-Berichten), und 1 von 40 leidet unter einer geistigen Behinderung. Daher weisen 3 bis 5 von % aller Geburten eine Entwicklungsanomalie auf oder werden eine solche entwickeln, von denen mindestens 25\u201350 von % genetischen oder genomischen Ursprungs sind. Diese riesige Population stellt in Wirklichkeit eine Ansammlung einer sehr gro\u00dfen Anzahl von einzeln seltenen Erkrankungen dar, die eine extreme Vielfalt an Ursachen und Ph\u00e4notypen aufweisen. Der Zust\u00e4ndigkeitsbereich und das Fachgebiet dieses ITHACA-Zentrums umfassen:<\/p>\n\n\n\n

    \n
  • \u00fcber 5.500 dysmorphe Syndrome und Syndrome mit multiplen angeborenen Anomalien (MCA), darunter \u00fcber 3.000 monogene Erkrankungen, alle Chromosomenanomalien (von denen die meisten nur mittels Array-Technologien nachweisbar sind), multifaktorielle und sporadische dysmorphe Anomalien sowie Embryo-Fetopathien umweltbedingten Ursprungs<\/li>\n\n\n\n
  • >3.000 monogene und Hunderte chromosomale Formen der geistigen Behinderung mit oder ohne begleitende Autismus-Spektrum-St\u00f6rung (ASD)<\/li>\n<\/ul>\n\n\n\n

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