{"id":384,"date":"2022-02-08T12:44:38","date_gmt":"2022-02-08T11:44:38","guid":{"rendered":"https:\/\/ern-ithaca.eu\/?post_type=expert-centers&#038;p=384"},"modified":"2025-02-26T11:44:56","modified_gmt":"2025-02-26T10:44:56","slug":"ern-ithaca-lille-center","status":"publish","type":"expert-centers","link":"https:\/\/ern-ithaca.eu\/de\/about-us\/expert-centers\/ern-ithaca-lille-center\/","title":{"rendered":"ERN-ITHACA \u2013 Lille Center"},"content":{"rendered":"<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"191\" height=\"156\" src=\"https:\/\/ern-ithaca.eu\/wp-content\/uploads\/2022\/02\/image003-1.jpg\" alt=\"\" class=\"wp-image-7200\" style=\"aspect-ratio:1;width:357px;height:auto\"\/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Clinique de g\u00e9n\u00e9tique Guy Fontaine<\/strong><br>Centres de r\u00e9f\u00e9rence maladies rares&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Anomalies du d\u00e9veloppement de l\u2019interr\u00e9gion Nord-Ouest<\/li>\n\n\n\n<li>Anomalies du d\u00e9veloppement de l\u2019interr\u00e9gion Ile-de-France \u2013 anomalies des membres<\/li>\n\n\n\n<li>D\u00e9ficiences intellectuelles de causes rares<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Clinique de Neurop\u00e9diatrie<\/strong><br>Centres de r\u00e9f\u00e9rence maladies rares Malformations et maladies cong\u00e9nitales du cervelet&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">H\u00f4pital Calmette, b\u00e2timent Paul Boulanger<br>Boulevard du professeur Jules Leclercq<br>59037 Lille Cedex France<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.chu-lille.fr\/\">Website<\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:56px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"lead\">Blei<\/h2>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:15%\">\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"530\" height=\"733\" src=\"https:\/\/ern-ithaca.eu\/wp-content\/uploads\/2022\/02\/Dr-Florence-PETIT.jpeg\" alt=\"\" class=\"wp-image-386\" srcset=\"https:\/\/ern-ithaca.eu\/wp-content\/uploads\/2022\/02\/Dr-Florence-PETIT.jpeg 530w, https:\/\/ern-ithaca.eu\/wp-content\/uploads\/2022\/02\/Dr-Florence-PETIT-434x600.jpeg 434w\" sizes=\"auto, (max-width: 530px) 100vw, 530px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:85%\">\n<p class=\"wp-block-paragraph\"><strong>Pr Florence Petit<\/strong> (Clinique de G\u00e9n\u00e9tique Guy Fontaine)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Telefon<\/strong>: +33 (0)3 20 44 49 11<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Fax<\/strong>: +33 (0)3 20 44 49 01<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>E-Mail<\/strong>:&nbsp;<a href=\"mailto:clad@chru-lille.fr\">clinique.genetique@chu-lille.fr<\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:56px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"scope\">Geltungsbereich<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The area of expertise of the Lille Centre of the ITHACA European Reference Network (ERN) covers all syndromes exhibiting developmental anomalies and\/or intellectual disability (ID). About 1\/40 newborn has a congenital malformation (261\/10000 fetuses and newborn following EuroCAt reports), and 1\/40 has ID. Therefore, 3 to 5 % of all human births show or will develop a developmental anomaly, among which at least 25-50% are of genetic or genomic origin. This huge population represents actually the addition of a very large number of individually rare disorders showing an extreme diversity of causes and phenotypes. The scope of expertise of Lille ITHACA Centre includes:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Over 5500 dysmorphic and multiple congenital anomalies (MCA) syndromes (listed in the London Dysmorphology Database), among which over 3000 monogenic diseases, all chromosome abnormalities (most of them only detectable through array technologies), multifactorial, sporadic dysmorphological anomalies and embryofetopathies of environmental origin<\/li>\n\n\n\n<li>Over 1500 monogenic and hundreds chromosomal forms of ID with or without autism spectrum disorder (ASD).<\/li>\n<\/ul>\n\n\n\n<div style=\"height:56px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"service-to-patients\">Dienst am Patienten<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The Centre contributes to the care to patients by offering clinical diagnosis, genetic testing, familial screening, genetic counseling, neuropsychological and neuropsychiatric evaluation, prenatal diagnosis, follow up and coordination of the day care and reeducation of patients, and therapeutic assays in the field of developmental anomalies, in connexion with two National Heathcare networks (AnDDI-Rares and DefiScience).<\/p>\n\n\n\n<div style=\"height:56px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"organization-of-the-ithaca-ern-lille-centre\">Organization of the ITHACA ERN \u2013 Lille Centre<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The University Hospital of Lille (Lille CHU) is providing care for more than 4.2 million inhabitants. Located on one unique campus, it is one of the largest university hospitals in France (over 3000 beds) with one of the biggest maternity wards of France (over 5500 births\/year) and pediatric hospitals (over 210 pediatric beds). Lille CHU offers full coverage of general and specialized cares in particular:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>A Department of clinical genetics offering genetic consultations and coordinated medical, paramedical psychological and social care for children, adults, and pregnant women with developmental anomalies (with or without ID) and their families. This Department is included in a large Bio-Pathology pole with genetic, fetal pathology and other laboratories.<\/li>\n\n\n\n<li>A pediatric hospital comprising several departments as those for child neurology (offering multidisciplinary diagnostic and care for ID and ASD children), child endocrinology, child metabolic disorders, pediatric cardiology, child nephrology, pediatric surgery \u2026<\/li>\n\n\n\n<li>A department of child psychiatry offering multidisciplinary diagnosis and care for ASD children.<\/li>\n\n\n\n<li>Prenatal diagnosis facilities and one of the two regional centers for prenatal diagnosis<\/li>\n\n\n\n<li>Full technical support, including classic medical laboratories, medical imaging, biological investigations, electrophysiology, genetic investigation (arrays, NGS), fetal pathology.<\/li>\n\n\n\n<li>Strong association with research institutes and several research units<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Moreover, owing to the importance of the geographical area and the population covered, the Lille Centre\u2019s team offers decentralized consultations in several hospitals in North of France (Arras, Calais, Dunkerque, Lens and Valenciennes)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Furthermore, it has developed a particular expertise on limb malformation at the clinical and molecular levels, providing diagnosis advices for these malformations to French and Foreign colleagues (over 400\/year).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Finally, the Lille Centre has a strong association with teaching (Lille University including Faculty of Medicine, Dental Surgery, Midwives, Physiotherapists \u2026) and research. The centre coordinates a research team on developmental diseases focusing on Limb defects and ID and collaborates with several INSERM or CNRS units.<\/p>","protected":false},"featured_media":0,"template":"","tags":[],"country":[6],"center-status":[15],"class_list":["post-384","expert-centers","type-expert-centers","status-publish","hentry","country-france","center-status-full-member"],"acf":{"name-city":"Lille Center","representative":"Pr Florence Petit ","latitude":"50.631290 ","longitude":"3.062750","keywords-search":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ERN-ITHACA \u2013 Lille Center - ERN ITHACA<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ern-ithaca.eu\/de\/about-us\/expert-centers\/ern-ithaca-lille-center\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ERN-ITHACA \u2013 Lille Center - 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