{"id":368,"date":"2022-02-08T11:30:22","date_gmt":"2022-02-08T10:30:22","guid":{"rendered":"https:\/\/ern-ithaca.eu\/?post_type=expert-centers&p=368"},"modified":"2025-06-11T13:55:55","modified_gmt":"2025-06-11T11:55:55","slug":"ern-ithaca-zagreb-center","status":"publish","type":"expert-centers","link":"https:\/\/ern-ithaca.eu\/es\/about-us\/expert-centers\/ern-ithaca-zagreb-center\/","title":{"rendered":"ERN-ITHACA \u2013 Centro de Zagreb"},"content":{"rendered":"
\"\"<\/figure>\n\n\n\n

Hospital Infantil de Zagreb<\/strong>
Calle Vjekoslav Klai\u0107, 16
10 000, Zagreb
CROACIA<\/p>\n\n\n\n

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P\u00e1gina web<\/a><\/div>\n<\/div>\n\n\n\n
<\/div>\n\n\n\n

Plomo<\/h2>\n\n\n\n
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\"\"<\/figure>\n<\/div>\n\n\n\n
\n
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\n

Prof. adjunta Dra. Iva Hojsak<\/strong><\/p>\n\n\n\n

Tel\u00e9fono: +385 (1) 4600 100<\/p>\n\n\n\n

Fax: +385(1) 4826 053<\/p>\n\n\n\n

Correo electr\u00f3nico: kdb@kdb.hr<\/a><\/p>\n<\/div>\n\n\n\n

\n

Dra. Ljubica Odak<\/strong><\/p>\n<\/div>\n<\/div>\n\n\n\n

<\/p>\n<\/div>\n<\/div>\n\n\n\n

<\/div>\n\n\n\n

\u00c1mbito de aplicaci\u00f3n<\/h2>\n\n\n\n

El \u00e1mbito de especializaci\u00f3n de nuestro centro, como miembro de la Red Europea de Referencia (ERN) ITHACA, abarca todos los s\u00edndromes que presentan anomal\u00edas del desarrollo y\/o discapacidad intelectual (DI). Aproximadamente 1 de cada 40 reci\u00e9n nacidos presenta una malformaci\u00f3n cong\u00e9nita (261 de cada 10 000 fetos y reci\u00e9n nacidos, seg\u00fan los informes de EuroCAt), y 1 de cada 40 presenta DI. Por lo tanto, entre 3 y 5 % de todos los nacimientos humanos presentan o desarrollar\u00e1n una anomal\u00eda del desarrollo, de las cuales al menos entre 25 y 50 % son de origen gen\u00e9tico o gen\u00f3mico. Esta enorme poblaci\u00f3n representa, en realidad, la yuxtaposici\u00f3n de un n\u00famero muy elevado de trastornos raros a nivel individual que presentan una diversidad extrema de causas y fenotipos. La competencia y el \u00e1mbito de especializaci\u00f3n de este centro ITHACA incluyen:<\/p>\n\n\n\n

    \n
  • m\u00e1s de 5.500 s\u00edndromes dism\u00f3rficos y de anomal\u00edas cong\u00e9nitas m\u00faltiples (MCA), entre los que se incluyen m\u00e1s de 3.000 enfermedades monog\u00e9nicas, todas las anomal\u00edas cromos\u00f3micas (la mayor\u00eda de ellas detectables \u00fanicamente mediante tecnolog\u00edas de microarrays), anomal\u00edas dism\u00f3rficas multifactoriales y espor\u00e1dicas, y embriopat\u00edas de origen ambiental<\/li>\n\n\n\n
  • >3.000 formas monog\u00e9nicas y cientos de formas cromos\u00f3micas de discapacidad intelectual, con o sin trastorno del espectro autista (TEA) asociado<\/li>\n<\/ul>\n\n\n\n
    <\/div>\n\n\n\n

    Atenci\u00f3n a los pacientes<\/h2>\n\n\n\n

    El Hospital Infantil de Zagreb (Klinika za dje\u010dje bolesti Zagreb \u2013 KDB) ofrece atenci\u00f3n quir\u00fargica integral, as\u00ed como seguimiento cl\u00ednico y ambulatorio pedi\u00e1trico a todos los pacientes con anomal\u00edas cong\u00e9nitas \u2014excepto las cardiopat\u00edas\u2014 desde el nacimiento hasta la edad adulta. La atenci\u00f3n postoperatoria se lleva a cabo a trav\u00e9s de la unidad de cuidados intensivos y el seguimiento ambulatorio.<\/p>\n\n\n\n

    El Departamento de Gen\u00e9tica M\u00e9dica y Salud Reproductiva ofrece evaluaci\u00f3n cl\u00ednica, pruebas gen\u00e9ticas y asesoramiento gen\u00e9tico para diversos trastornos gen\u00e9ticos a pacientes de todas las edades. La evaluaci\u00f3n rutinaria incluye un examen cl\u00ednico realizado por un pediatra o un genetista m\u00e9dico, datos sobre los antecedentes familiares, antropometr\u00eda (peso, estatura y per\u00edmetro craneal), an\u00e1lisis del \u00e1rbol geneal\u00f3gico, evaluaci\u00f3n otorrinolaringol\u00f3gica y oftalmol\u00f3gica, as\u00ed como la valoraci\u00f3n por parte de un neur\u00f3logo pedi\u00e1trico, un psiquiatra, logopedas y terapeutas ocupacionales, y otros especialistas en funci\u00f3n de las caracter\u00edsticas cl\u00ednicas. El KDB tambi\u00e9n ofrece logopedia y terapia ocupacional, tratamiento de trastornos alimentarios y fisioterapia. El Laboratorio de Gen\u00e9tica M\u00e9dica lleva a cabo m\u00e9todos de citogen\u00e9tica cl\u00e1sica, cariotipado molecular (MLPA \u2014amplificaci\u00f3n multiplex dependiente de ligaci\u00f3n\u2014, MS-MLPA y microarray cromos\u00f3mico), an\u00e1lisis gen\u00f3mico, secuenciaci\u00f3n cl\u00ednica del exoma, pruebas gen\u00e9ticas de panel para la p\u00e9rdida auditiva y la sordera, s\u00edndromes gen\u00e9ticos y pruebas gen\u00e9ticas espec\u00edficas para enfermedades monog\u00e9nicas: distrofia muscular de Duchenne-Becker, s\u00edndrome de Rett, acondroplasia\/hipocondroplasia, s\u00edndrome del X fr\u00e1gil, trastornos del desarrollo neurol\u00f3gico, enfermedades del tejido conectivo, genodermatosis, enfermedades card\u00edacas y renales, trastornos cong\u00e9nitos de la vista y la audici\u00f3n.\u00a0 Cada a\u00f1o se realizan pruebas gen\u00e9ticas a 2 300 pacientes, mientras que se lleva a cabo una evaluaci\u00f3n diagn\u00f3stica cl\u00ednica integral a 1 700 pacientes con anomal\u00edas cong\u00e9nitas, autismo o discapacidad intelectual.<\/p>\n\n\n\n

    Como parte de la red EUROCAT (red europea de registros poblacionales), se lleva a cabo un seguimiento epidemiol\u00f3gico de las anomal\u00edas cong\u00e9nitas en cinco regiones croatas, que abarcan aproximadamente el 18% de la poblaci\u00f3n croata.<\/p>\n\n\n\n

    <\/div>\n\n\n\n

    Organizaci\u00f3n del centro<\/h2>\n\n\n\n

    El KDB es el hospital pedi\u00e1trico m\u00e1s grande y completo de Croacia. Guiado por los principios de la medicina pedi\u00e1trica integrada, en colaboraci\u00f3n con instituciones asociadas y acad\u00e9micas, y de conformidad con la Convenci\u00f3n Internacional sobre los Derechos del Ni\u00f1o (UNCRC), el Hospital Infantil de Zagreb (KDB) presta asistencia m\u00e9dica hospitalaria a unos 7 000 ni\u00f1os al a\u00f1o. Cada a\u00f1o, alrededor de 25 000 ni\u00f1os reciben seguimiento o atenci\u00f3n ambulatoria.<\/p>\n\n\n\n

    El KDB atiende las necesidades sanitarias de los ni\u00f1os en todo el territorio de la Rep\u00fablica de Croacia (con una poblaci\u00f3n total de unos 4 millones de personas), as\u00ed como en los pa\u00edses vecinos. El tratamiento de los pacientes se lleva a cabo mediante atenci\u00f3n hospitalaria, con una capacidad de 75 camas en el Departamento de Pediatr\u00eda, y a trav\u00e9s de consultas externas especializadas en la Policl\u00ednica. Como parte integrante de la Cl\u00ednica Pedi\u00e1trica, existe una Policl\u00ednica de Psiquiatr\u00eda Infantil y Adolescente que se encarga del diagn\u00f3stico y el tratamiento de los trastornos del desarrollo neurol\u00f3gico, as\u00ed como de diversos trastornos psiqui\u00e1tricos que se manifiestan durante la infancia.<\/p>\n\n\n\n

    La Cl\u00ednica de Cirug\u00eda Pedi\u00e1trica del KDB es el centro de cirug\u00eda pedi\u00e1trica m\u00e1s grande de la Rep\u00fablica de Croacia (83 camas) y ofrece intervenciones quir\u00fargicas rutinarias, as\u00ed como cirug\u00edas de anomal\u00edas cong\u00e9nitas m\u00e1s complejas y poco frecuentes, salvo los defectos card\u00edacos. La unidad de cuidados intensivos proporciona atenci\u00f3n postoperatoria a los pacientes pedi\u00e1tricos y quir\u00fargicos m\u00e1s graves. Como parte de la atenci\u00f3n sanitaria integral, tambi\u00e9n se ofrecen servicios de diagn\u00f3stico radiol\u00f3gico que abarcan ecograf\u00edas, radiograf\u00edas, resonancia magn\u00e9tica y tomograf\u00eda computarizada. El servicio de diagn\u00f3stico de laboratorio permite realizar diversos tipos de an\u00e1lisis hematol\u00f3gicos, bioqu\u00edmicos y microbiol\u00f3gicos.<\/p>\n\n\n\n

    Gracias a su dilatada experiencia y a la calidad de su atenci\u00f3n sanitaria, el KDB es la sede de tres centros de referencia del Ministerio de Sanidad de la Rep\u00fablica de Croacia, as\u00ed como centro de formaci\u00f3n para estudiantes y residentes. En colaboraci\u00f3n con instituciones acad\u00e9micas nacionales e internacionales, el KDB participa en proyectos de investigaci\u00f3n cient\u00edfica. Los resultados de estas actividades se presentan en congresos cient\u00edficos y profesionales y se publican en revistas indexadas (Medline, Current Contents).<\/p>","protected":false},"featured_media":0,"template":"","tags":[],"country":[49],"center-status":[15],"class_list":["post-368","expert-centers","type-expert-centers","status-publish","hentry","country-croatia","center-status-full-member"],"acf":{"name-city":"Zagreb Center","representative":"Dr Mijana Kero ","latitude":"45.815011 ","longitude":"15.981919","keywords-search":""},"yoast_head":"\nERN-ITHACA \u2013 Zagreb Center - ERN ITHACA<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ern-ithaca.eu\/es\/about-us\/expert-centers\/ern-ithaca-zagreb-center\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ERN-ITHACA \u2013 Zagreb Center - ERN ITHACA\" \/>\n<meta property=\"og:description\" content=\"Children’s Hospital ZagrebUl. 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