Solve-RD still has 740,000 EUR available to support projects for functional validation of new disease genes or variants.
Since October 21th, the 6th call for Connection Applications within the European Rare Disease Models & Mechanisms (RDMM-Europe) brokerage service is opened.
This brokerage service aims to connect Solve-RD clinicians & scientists with model organism investigators and rewards Seeding Grants of 20,000 EUR to model organism investigators to study and validate a new disease causing variant that was found within Solve-RD.
Solve RD would like to encourage all partners and associated partners who found an interesting new variant within the course of Solve-RD and would like to have this further investigated in a model organism to apply.
For this call SOLVE RD accepts several applications per ERN but would restrict the number of applications per working group to a maximum of two.
For your application please consider the following:
- GPAP and PhenoTips IDs of the respective patients are mandatory (pheno- and genotypic data have to be uploaded to RD-Connect).
- Make sure that you have made every effort to identify additional patients with similar variants in your candidate gene. Single family cases have been a major point of criticism of the CAC committee in previous Connection Applications.
- Please specify the type of validation that you want to have performed. The application template has been revised to make this information mandatory.