MOOC “bioinformatics”

The MOOC BiG “Introduction to BioInformatics and Genomic Medicine” aims to address all the bioinformatics aspects necessary for the production and interpretation of High-Throughput Sequencing (HTS) or Next Generation Sequencing (NGS) data within a clinical genetics laboratory with examples of rare diseases and oncogenetics.

This introductory course is primarily intended for health professionals using genomics. Its objective is to provide specific and adapted contents to enable them to understand the different steps from phenotyping to molecular diagnosis and to have a critical eye on the analyses while taking into account the pitfalls and limits of NGS. Designed by a French team, it will also present the functioning of the genomic pathway in France.

For the general public or the curious, the objective is to make them aware of a technique that plays an increasingly important role in the diagnosis of genetic diseases.

This MOOC is organised by the French University Paris-Cité and is supported by the ERN.

Format

The MOOC will be self paced. Learners will have access to all the contents from the beginning. Each teaching unit will explore a step of NGS processing by focusing on different themes with videos in french subtitled in English, texts and self-correction exercises. Interactive content, such as python-based jupyter notebooks will permit us to go further in genome interpretation and programming.  

As genomic medicine and NGS require a wide range of skills, we suggest you make your own path through the MOOC according to your profile and learning objectives.

– For the beginners, the introductive unit “Back to Basics” will guide you through the basics of genetics, bioinformatics and genomic medicine.
– Unit 1 sets the context and will be of interest to all learners, with the example of the French model.
– Unit 2 is at the crossroads between clinics, biology, bioanalysis and bioinformatics. It will be of interest to all those who will be prescribing or interpreting genetic results as well as bioinformatics pipeline designers.
– Units 3, 4 and 5 are increasingly focused on bioinformatics. Bioinformaticians will be in familiar territory, it may be more difficult for those who do not handle these tools on a daily basis.

In short, pick what you find most useful or follow the guide!

In addition to the courses, you’ll find a forum dedicated to online exchanges between learners and pedagogical team.

To know more about the MOOC and to enroll to the course BEFORE NOV. 30: BiG – Introduction to BioInformatics and Genomic Medicine – Course – FUN MOOC