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Targeted gene under study:

* 605802 / # 235730 / ORPHA:2152

Abstract

The postnatal phenotype of Mowatt-Wilson syndrome (ZEB2) is well known. However, only a few fetal case reports with antenatal description have been reported in the literature. Following a call for collaboration via Soffoet (France), we have collected several fetal cases. In order to refine the prenatal phenotypic description of Mowatt-Wilson syndrome, we are interested in fetuses carrying pathogenic or probably pathogenic variants in ZEB2 with autopsy if possible and detailed antenatal data of your patients.

Coordinating clinician

Cindy Colson – Cindy.colson@chu-lille.fr

Institution

Service Génétique, CHU Lille, France

Specific requirements beyond clinical data and genotype data sharing:

1- Re-analysis of DNA samples: No

2- Resampling of patients: No

3- Linked to a translational/basic research project: Yes/No